Robust Multi-modal Registration of Cerebral Vasculature

The assessment of neurological disorders benefits from a precise visualization of the vasculature and the surrounding brain tissue, leading to a more comprehensive understanding of the anatomical structures and pathological changes. While multi-modal registration of neuroimages has been extensively researched, existing methods face limitations regarding the alignment of angiographic and structural images and rely heavily on a good initial alignment. To address suboptimal initial alignments, manual or fiducial-based global alignment methods are commonly employed in clinical practice.